In complement to an effective vaccine, development of potent anti-HIV microbicides remains an important priority.We have previously shown that the miniCD4 M48U1, a functional mimetic of sCD4 presented on a 27 amino-acid stable scaffold, inhibits a broad range of HIV-1 isolates at sub-nanomolar concentrations in cellular models.Here, we report that
Edible flowers have been consumed from ancient times and it was believed to deliver medicinal properties.This study explored some common edible flowers from Assam, India, such as Night Jasmine (Nyctanthus arbortristis), Drumstick (Moringa oleifera), Pumpkin (Cucurbita spp.), and Nongmangkha (Phlogacanthus thyrsiflorus), to assess their nutritional
Significant progress has been made in generating copyright images and videos.Forged videos generated by deepfaking have been widely spread and have caused severe societal impacts, which stir up public concern Nits Treatment about automatic deepfake detection technology.Recently, many deepfake detection methods based on forged features have been pro
This paper proposes one new design method for a higher order extended Kalman filter based on combining maximum correlation entropy with a Taylor network system to create a nonlinear random dynamic system with modeling errors and unknown statistical properties.Firstly, the transfer function and measurement function are transformed into a nonlinear r